STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95683.1Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein. (434 aa)    
Predicted Functional Partners:
CAZ95679.1
Rubredoxin family protein; Conserved protein containing a C-terminal Rubredoxin-like domain. The most conserved feature of the rubredoxin-like domain is the cluster of four cysteines involved in iron binding (Cys-x-x-Cys-x(n)-Cys-x-x-Cys). This domain folds into a short three-stranded antiparallel beta-sheet and a number of loops; Localized in the cytoplasm; Family membership.
 
     0.838
CAZ95694.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments and an N-terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Localized in the cytoplasmic membrane; Family membership.
 
     0.752
CAZ95689.1
Nitrate/nitrite-specific MFS transporter protein; Putatively involved in the uptake of nitrate or extrusion of nitrite; The proteins contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Function unclear.
 
     0.722
narB/nirB
Respiratory nitrate/nitrite reductase; Bifunctional enzyme involved in the denitrification processes (nitrate respiration). It contains in its N-terminal part a nitrate reductase module required for nitrate assimilation (reducing nitrate to nitrite) using molybdopterin and 1 4Fe-4S cluster as cofactors and in its C-terminal part a nitrite reductase module required for nitrite assimilation (reducing nitrite to ammonia) using FAD, 4Fe-4S cluster and siroheme as cofactors; Belongs to Belongs to the prokaryotic molybdopterin-containing oxidoreductase family and to the nitrite and sulfite r [...]
 
     0.698
nrtD
Nitrate-specific ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Probably part of a high-affinity binding-protein-dependent transport system for nitrate. Probably responsible for energy coupling to the transport system; Family membership.
 
     0.695
nrtC
Nitrate-specific ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Probably part of a high-affinity binding-protein-dependent transport system for nitrate. Probably responsible for energy coupling to the transport system; Family membership.
       0.681
nrtB
Nitrate-specific BPD transport, permease component; Probably part of a high-affinity binding-protein-dependent (BPD) transport system for nitrate; probably responsible for the translocation of the substrate across the membrane; Localized in the cytoplasmic membrane by six transmembrane segments; High confidence in function and specificity.
 
     0.658
CAZ95682.1
Response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA- binding activity (here a LuxR-type HTH domain) that acts as transcriptional regulator; Family membership.
 
     0.632
nirD
Nitrite reductase, small subunit; Protein that consists of a Rieske domain; The rieske domain has a 2Fe-2S centre; Associates with NirB and is required for activity reductase of NirB; High confidence in function and specificity.
 
     0.581
nrtA
Essential component of the nitrate-transporting system. May be the substrate-binding protein; Lipoprotein putatively anchored in the outer membrane or in the cytoplasmic membrane (or in both membranes) by its N-terminal lipidic residue (peripheral membrane protein); High confidence in function and specificity.
       0.533
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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