STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xylA-2Xylose isomerase is involved in xylose metabolism. It catalyzes the conversion of D-xylose into D-xylulose. It forms a homotetramer and binds 2 magnesium ions per subunit. Localized in the cytoplasm; High confidence in function and specificity. (441 aa)    
Predicted Functional Partners:
xylB-2
Xylulose kinase is involved in xylose catabolism. It catalyzes the reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate. Localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.996
uxuB
D-mannonate oxidoreductase or Fructuronate reductase catalyzes the NAD-dependent reduction of fructuronate into mannonate; Belongs to the Long-chain mannitol dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.914
scrK1
Fructokinase catalyzes the transfert of phosphate group from ATP to convert the fructose to fructose-6-phosphate, which is an entry point into glycolysis (Embden-Meyerhof pathway) via conversion into glucose-6-phosphate; Belongs to the carbohydrate kinase pfkB superfamily, bacterial fructokinase family; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.908
scrK2
Fructokinase catalyzes the transfer of a phosphate group from ATP to convert the fructose to fructose-6-phosphate, which is an entry point into glycolysis (Embden-Meyerhof pathway) via conversion into glucose-6-phosphate; Belongs to the carbohydrate kinase PfkB superfamily, bacterial fructokinase family; Localized in the cytoplasm; Family membership.
    
 0.908
talA1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
     
 0.869
CAZ96825.1
Sugar kinase; Enzymes that catalyze the transfer of phosphoryl group on a sugar from ATP, producing a phosphorylated sugar; Belongs to the ROK family; localized in the cytoplasm; Specificity unclear.
    
 0.831
CAZ94398.1
Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership.
    
 0.831
glkA
Glucokinase is involved in the first step of the glycolysis (Embden-Meyerhof pathway). It phosphoryles the D-glucose to D-glucose 6-phosphate. This reaction consumes ATP, but it acts to keep the glucose concentration low, promoting continuous transport of glucose into the cell through the cytoplasmic membrane transporters; Localized in the cytoplasm; High confidence in function and specificity.
     
 0.817
algD
GDP-mannose 6-dehydrogenase catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid. In Pseudomonas aeruginosa, this activated sugar is the precursor for alginate polymerization. AlgD belongs to the UDP-glucose/GDP- mannose dehydrogenase family, a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate. Localized in the cytoplasm; High confidence in function and specificity.
     
 0.812
lacZ
Beta-galactosidase, family GH2; Enzyme that catalyzes the hydrolysis of the beta- 1, 4 linkage at the terminal non-reducing of beta-D-galactosides, releasing a beta-D-galactose residue; Belongs to the family 2 of glycoside hydrolases (GH2); Signal peptide cleaved between residues 28 and 29; Possibly localized in the outer membrane; High confidence in function and specificity.
    
 0.810
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.