STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdtCdTDP-D-Fucp3N acetylase catalyzes the transfer of an acetyl group from acetyl-CoA to dTDP-D-Fucp3N to form dTDP-D-Fucp3NAc. FdtC is involved in the biosynthesis of lipopolysaccharides; Belongs to the o-acetyltransferase family; Contains five tandem repeats of a [LIV]-G-X(4) hexapeptide, which folds as a left-handed parallel beta helix; Localized in the cytoplasm; High confidence in function and specificity. (193 aa)    
Predicted Functional Partners:
fdtB
The dTDP-6-deoxy-D-xylo-hex-3-ulose aminase aminates specifically dTDP-6-deoxy-D-xylo-hex-3-ulose to form dTP-D-Fucp3N. FdtB, involved in the biosynthesis of lipopolysaccharides, requires pyridoxal-phosphate and L-glutamate as cofactors; Belongs to the DegT/DnrJ/EryC1/StrS aminotransferase family, PLP dependent aminotransferase superfamily; Localized in the cytoplasm; High confidence in function and specificity.
  
  0.992
wecB
UDP-N-acetylglucosamine 2-epimerase converts the UDP-N-acetyl-D-glucosamine to UDP-N-acetyl-D-mannosamine. WecB is involved in amino sugar metabolism and in the lipopolysaccharide biosynthesis; Belongs to the UDP-Glycosyltransferase/glycogen phosphorylase superfamily; Localized in the cytoplasm; High confidence in function and specificity.
 
  
  0.986
porR
PorR belongs to the DegT/DnrJ/EryC1/StrS aminotransferase family, which is included in the pyridoxal-phosphate (PLP)-dependent aminotransferase superfamily. PorR is involved in the biosynthesis of cell surface polysaccharides. In Porphyromonas gingivalis the porR mutant showed a pleiotropic phenotype: loss of pigmentation, delayed maturation of fimbrillin, preferential presence of Rgp and Kgp proteinases in culture supernatants, and no haemagglutination; Specificity unclear.
  
  0.971
wbpB
WbpB is a NAD(P)-dependent oxidoreductase involved in lipopolysaccharide biosynthesis; Belongs to the GFO/IDH/MOCA family; Adopts a Rossmann fold; Localized in the cytoplasm; Specificity unclear.
 
     0.932
wzxA
O-antigen translocase; WzxA translocates undecaprenylpyrophosphate-bound O-antigen subunits from the cytoplasm to the periplasm. Wzx is an integral membrane protein involved in lipopolysaccharide biosynthesis; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
     0.883
CAZ95796.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.781
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
   
   0.750
CAZ95197.1
NAD(P)-dependent oxidoreductase that adopts a Rossmann fold; belongs to the GFO/IDH/MOCA family; Localized in the cytoplasm; Specificity unclear.
     0.736
rmlD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
    0.730
capJ
CapJ is involved in the capsular polysaccharide biosynthesis. Its features three tandem repeats of a [LIV]-G-X(4) hexapeptide, which folds as a left-handed parallel beta helix; Belongs to the o-acetyltransferase family; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Specificity unclear.
       0.692
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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