STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94247.1The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership. (341 aa)    
Predicted Functional Partners:
CAZ97694.1
LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of catabolic, metabolic and transport operons; Contains a N-terminal LacI-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a C-terminal domain involved in the binding of inducers; Localized in the cytoplasm; Family membership.
  
     0.680
gltA-2
Glutamate synthase [NADPH] large chain; Glutamate synthase is a key enzyme in the early stages of the assimilation of ammonia. It is a complex iron-sulfur flavoprotein catalyzing the reductive transfer of the amido nitrogen from L-glutamine to 2-oxoglutarate to form two molecules of L-glutamate via intramolecular channelling of ammonia from the amidotransferase domain to the FMN-binding domain. Glutamate synthase forms an aggregate of 4 catalytic active heterodimers, consisting of a large and a small subunit (GltB). GltA binds as cofactors a 3Fe-4S cluster, a FAD and a FMN. Localized i [...]
    
 
 0.593
xylB-2
Xylulose kinase is involved in xylose catabolism. It catalyzes the reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate. Localized in the cytoplasm; High confidence in function and specificity.
 
 
 
 0.535
rbsB
Ribose ABC importer, periplasmic component; RbsB is the D-ribose-binding protein involved in the high-affinity D-ribose membrane transport system; Belongs to the bacterial solute-binding protein 2 family; Seems to have a uncleavable signal sequence; Localized in the cytoplasmic membrane and exposed in the periplasmic space; High confidence in function and specificity.
 
  
 0.453
talA1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
   
 
 0.448
rbsC
Ribose ABC importer, permease component; Part of the binding-protein-dependent ABC transporter system for D-ribose. Probably responsible for the translocation of the substrate across the membrane; Contains seven transmembrane segments; Belongs to the binding-protein-dependent transport system permease family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
  
 0.432
xylA-2
Xylose isomerase is involved in xylose metabolism. It catalyzes the conversion of D-xylose into D-xylulose. It forms a homotetramer and binds 2 magnesium ions per subunit. Localized in the cytoplasm; High confidence in function and specificity.
     
 0.414
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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