STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95844.1Conserved hypothetical protein; Localized in the cytoplasm. (319 aa)    
Predicted Functional Partners:
gldI
GldI, lipoprotein required for gliding motility, contains a Peptidyl-prolyl cis-trans isomerase (PPIase) domain; PPIases catalyze the peptidyl-prolyl isomerisation of the peptide bond preceding proline that is stabilised in the cis conformation in oligopeptides; GldI may be involved in folding cell envelope protein components of the motility machinery; Signal peptide cleaved between the residues 14 and 15; Localized in the outer membrane or/and cytoplasmic membrane; High confidence in function and specificity.
  
     0.753
CAZ95216.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.750
CAZ94558.1
Conserved hypothetical protein; Localized in the cytoplasm.
  
    0.742
ftsL
Hypothetical protein that could be FtsL involved in coupling of cell division and peptidoglycan physiology; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.731
CAZ97275.1
Small protein that contain a C-terminal Smr (Small MutS Related) domain; The Smr domain would act as a nicking endonuclease and would interact with the MutS-1 protein; Belongs to the DNA mismatch repair mutS family; Localized in the cytoplasm; Function unclear.
  
     0.710
sprE
The SprE protein could be involved in the gliding motility; Contains four tetratrico peptide repeats (TPRs). TPRs mediate proteinprotein interactions. TPR adopts a helixturnhelix arrangement, with adjacent TPR motifs packing in a parallel fashion, resulting in a spiral of repeating anti-parallel alpha-helices. SprE contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Function unclear.
  
     0.676
CAZ98751.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein.
 
  
 0.673
CAZ95348.1
Conserved hypothetical protein; Protein that consists of a LysE type translocator domain with six transmembrane segments; Probably localized in the cytoplasmic memmbrane.
  
    0.662
CAZ97281.1
Conserved hypothetical protein; Localized in cytoplasm.
  
     0.643
CAZ97872.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.634
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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