STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dprAThe protein Smf (or DprA) would be a new member of the recombination-mediator protein family, dedicated to natural bacterial transformation; Localized in the cytoplasm; High confidence in function and specificity. (367 aa)    
Predicted Functional Partners:
CAZ95478.1
Phosphoribosyltransferase carries out phosphoryl transfer reactions on 5-phosphoribosyl-alpha1-pyrophosphate, an activated form of ribose-5-phosphate. Its exact specificity is still unknown; Localized in the cytoplasm; Function unclear.
 
 
 0.908
CAZ95245.1
Competence proteins are essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane. This competence protein features eleven transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
  
 0.902
comM
ComM is induced during competence development. Not needed for DNA uptake. May be involved in a recombination step; Belongs to the Mg-chelatase subunits D/I family, ComM subfamily; Localized in the cytoplasm; High confidence in function and specificity.
 
 0.826
CAZ98713.1
Mg chelatase family protein; Protein displaying similarity with the C-terminal region of Mg chelatase subunit ChlI; Localized in the cytoplasm; Function unclear.
 
 0.821
CAZ94725.1
Conserved hypothetical membrane protein; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
  
 0.762
topA1
DNA topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
   
 0.757
CAZ95844.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.588
radC
RadC plays a role in repair of DNA damage after UV and X-ray irradiation in prokaryotes; RadC may function specifically in recombinational repair that is associated with the replication fork. Involved in DNA repair; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the UPF0758 family.
  
  
 0.582
CAZ94729.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.572
CAZ96259.1
Conserved hypothetical protein belonging to the UPF0102 family. localized in the cytoplasm.
 
    0.554
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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