Succinate dehydrogenase is a complex containing three subunits: a flavoprotein, an iron-sulfur protein and cytochrome b-558. It is involved in the citrate cycle and catalyzes the reaction: succinate + acceptor = fumarate + reduced acceptor. It uses a FAD as a cofactor. SdhC is the cytochrome b558 subunit. It binds two hemes. Features five transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.

Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

Lactaldehyde dehydrogenase catalyze the NAD-dependent oxidation of lactaldehyde into lactate. This protein is a tetramer. AldA is involved in the catabolism of L-fucose and L-rhamnose and is induced by these sugars. In aerobic condition, the lactaldehyde is produced by the cleavage of L-fucose or L-rhamnose; Belongs to the aldehyde dehydrogenase fold family; Localized in the cytoplasm; High confidence in function and specificity.

Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership.

Hypothetical membrane protein; Contains one N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein.

Rieske [2Fe-2S] iron-sulfur protein; Protein that contains an unknown function N-terminal domain and a C-terminal Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines that one Fe ion while the other Fe ion is coordinated by two conserved histidines; Prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Function unclear.

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3); High confidence in function and specificity.