STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94263.1This protein belongs to the family 105 of the glycoside hydrolases. These enzymes are involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. Asp104 is the putative catalytic residue (identical to Asp143 of the unsaturated rhamnogalacturonyl hydrolase from Bacillus subtilis, Itoh et al., 2006, BBRC 347, 10211029). Features a signal peptide cleaved between residues 20 and 21. Localized in the periplasm; Specificity unclear. (383 aa)    
Predicted Functional Partners:
CAZ94267.1
Conserved hypothetical lipoprotein; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein.
     0.911
CAZ97947.1
Conserved hypothetical protein; Localized in the cytoplasm.
     0.860
kduI1
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.850
idnO1
Gluconate-5-dehydrogenase; Also called 5-keto-D-gluconate 5-reductase; Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate using NADP as a coenzyme. Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
       0.775
CAZ94260.1
The Sugar permeases belong to the major facilitator superfamily (MFS) transporters that are single-polypeptide secondary carriers capable only of transporting small solutes (probably sugars in this case) in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Family membership.
 
     0.765
CAZ94259.1
Conserved hypothetical membrane protein; Contains a putaive lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein.
      0.751
CAZ97595.1
Conserved hypothetical protein; Localized in the cytoplasm.
     0.743
CAZ94264.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Probably localized in the cytoplasmic membrane; Family membership.
 
     0.613
bgaD
Beta-galactosidase, family GH2; Enzyme belonging to the family 2 of glycoside hydrolases (GH2) which catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing of beta-D-galactosides, releasing a beta-D-galactose residue; Signal peptide cleaved between residues 22 and 23; Localized in the periplasmic space; High confidence in function and specificity.
 
     0.590
CAZ94265.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (52-125) and the Plug module (141-255) acting as a channel gate; The signal peptide is cleaved between the residues 33 and 34; Family membership.
 
     0.570
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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