STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95978.1This conserved protein contains a N-terminal domain Localized in the cytoplasm; Family membership. (285 aa)    
Predicted Functional Partners:
gmkA
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
 0.937
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
     0.727
gltA-2
Glutamate synthase [NADPH] large chain; Glutamate synthase is a key enzyme in the early stages of the assimilation of ammonia. It is a complex iron-sulfur flavoprotein catalyzing the reductive transfer of the amido nitrogen from L-glutamine to 2-oxoglutarate to form two molecules of L-glutamate via intramolecular channelling of ammonia from the amidotransferase domain to the FMN-binding domain. Glutamate synthase forms an aggregate of 4 catalytic active heterodimers, consisting of a large and a small subunit (GltB). GltA binds as cofactors a 3Fe-4S cluster, a FAD and a FMN. Localized i [...]
  
    0.692
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
    0.609
CAZ95214.1
These transcriptional regulators consit of two domains: a N-terminal sigma 54 interaction domain that acts as an ATP binding domain (in its N-terminal part) and as sigma 54 binding domain with an ATPase activity (in its C-terminal part), and a Fis-type helix-turn-helix DNA-binding domain in their C-terminal section; Family membership.
  
     0.447
CAZ95977.1
Conserved hypothetical membrane protein; Contains a domain of unknown function (DUF1080) that may adopt a concavalin-like or glucanase-like fold founded in glycoside hydrolases; Putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Conserved hypothetical protein.
       0.444
CAZ98902.1
Conserved hypothetical protein. Localized in the cytoplasm.
  
  
 0.427
vacB
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
 
     0.424
rpoN
RNA polymerase sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. sigma-54 factors consist of three distinct regions: A conserved N-terminal glutamine-rich region (50 aa) that contains a potential leucine zipper motif. A region which is not conserved. A conserved C-terminal region (350 aa) that contains a second potential leucine zipper, a potential DNA-binding 'helix-turn-helix' motif and a perfectly conserved octapeptide whose function is not known; Localized in the cytoplasm; High confidenc [...]
 
     0.413
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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