STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zupTHeavy-metal cations permease; Mediates zinc uptake. May also transport other divalent cations; Contains three N-terminal and three C-terminal transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity. (273 aa)    
Predicted Functional Partners:
CAZ96007.1
Metal dependent transcriptional regulator binds two divalent metal effectors per monomer via an dimerization domain with two metal-binding sites, upon which allosteric changes occur that moderate binding to the cognate DNA operators of a target gene via a N-terminal DtxR-type HTH domain; Contains an C-terminal SH3-like domain that characterizes the Fe(II)-regulators. It may act to stabilizing the dimeric form of the repressor; Family membership.
  
  
 0.848
CAZ96006.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (26-104) and the Plug module (121-228) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; Putatively involved in the colicin 1A and 1B uptake; Family membership.
  
    0.557
CAZ96009.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains an N- terminal GAF domain; Seems localized in the cytoplasm; Family membership.
     
 0.467
sodA
Superoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.454
crtY
Lycopene cyclase; Catalyzes the double cyclization reaction which converts lycopene to beta-carotene; Involved in the carotenoid biosynthesis; contains a N-terminal transmembrane segment; Putatively localized in the cytoplasmic membrane; Family membership.
  
    0.454
CAZ96969.1
Conserved protein belonging to the NAD(P)-dependent epimerase/dehydratase family. Adopts a Rossmann fold. Localized in the cytoplasm; Function unclear.
  
    0.441
viuB
Siderophore-interacting proteins are involved in intracellular removal of iron from iron-siderophore complex. Induced by iron starvation; Contains a N-terminal FAD-binding domain; Localized in the cytoplasm; High confidence in function and specificity.
   
    0.432
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.