STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfbXO-antigen transporter; May be involved in the Lipopolysaccharide O antigen biosynthesis, translocating the nascent polysaccharidic O-antigen molecules and/or ligating them to lipid A core units; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Function unclear. (453 aa)    
Predicted Functional Partners:
wzcA
Tyrosine-protein kinase; May be involved in the production and the transport of exopolysaccharides; Contains a N-terminal transmembrane segment; Belongs to the etk/wzc family; Localized in the cytoplasmic membrane; Specificity unclear.
 
  
 0.841
algD
GDP-mannose 6-dehydrogenase catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid. In Pseudomonas aeruginosa, this activated sugar is the precursor for alginate polymerization. AlgD belongs to the UDP-glucose/GDP- mannose dehydrogenase family, a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate. Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.786
CAZ96045.1
Conserved protein involved in exopolysaccharide biosynthesis. Its exact function is unknown. Contains five transmembrane helices. Localized in the cytoplasmic membrane; Function unclear.
  
  
 0.766
CAZ96060.1
Glycosyltransferase, family GT4; Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm; Specificity unclear.
 
  
 0.759
CAZ96050.1
Conserved hypothetical membrane protein; Contains eleven transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.718
CAZ96054.1
Conserved hypothetical protein; Contains a domain of unknown function DUF354. This family mainly contains proteins from Archae; Localized in the cytoplasm.
 
   
 0.678
rmlB
dTDP-glucose 4,6-dehydratase converts the dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose. This enzyme is involved in the nucleotide sugar metabolism and in the lipopolysaccharide biosynthesis; Belongs to the NAD dependent epimerase/dehydratase family, Rossmann fold Superfamily; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.645
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.645
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.644
CAZ96046.1
Membrane protein likely involved in the export of expolysaccharide repeating units from the cytoplasm into the periplasm in a process analogous to O-unit export; Contains a C-terminal transmembrane helix; Prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the cytoplasmic membrane; Specificity unclear.
 
  
 0.572
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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