STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96080.1Conserved protein belonging to the NAD(P)-dependent sugar epimerase/dehydratase family, which is included in the Rossmann fold superfamily; Localized in the cytoplasm; Family membership. (334 aa)    
Predicted Functional Partners:
ugdH
UDP-glucose 6-dehydrogenase catalyzes the oxidation of UDP-glucose to UDP-glucuronate. Likely involves in EPS biosynthesis. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family, a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate; Localized in the cytoplasm; High confidence in function and specificity.
 0.976
galE
GalE interconverts UDP-glucose and UDP-galactose which are precursors of glucose- and galactose-containing exopolysaccharides (EPS). Belongs to the NAD dependent epimerase/dehydratase family, which is included in the Rossmann fold Superfamily; High confidence in function and specificity.
 
0.934
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
    
 0.902
CAZ96078.1
FAD-dependent amine oxidoreductase; The main role of amine oxidases is to provide a source of ammonium; Adopts a Rossmann fold; Uses FAD as prosthetic group; Localized in the cytoplasm; Specificity unclear.
 
  
 0.820
CAZ96074.1
Glycosyltransferase, family GT2; Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 2 of the glycosyltransferases (GT2); Contains two transmembrane helices in C-terminus; Localized in the cytoplasmic membrane; Specificity unclear.
 
   0.815
algD
GDP-mannose 6-dehydrogenase catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid. In Pseudomonas aeruginosa, this activated sugar is the precursor for alginate polymerization. AlgD belongs to the UDP-glucose/GDP- mannose dehydrogenase family, a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate. Localized in the cytoplasm; High confidence in function and specificity.
 
 0.753
CAZ96076.1
Carbohydrate esterase, family CE4; The carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. These proteins fold into a 7-stranded beta/alpha barrel; Contains a C-terminal transmembrane helix; Belongs to the family 4 of carbohydrate esterases (CE4); Localized in the cytoplasmic membrane; Specificity unclear.
 
  
 0.735
CAZ97895.1
Beta-(1,4)-galactosyltransferase, Family GT2; Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases. It is closely related to the beta-(1,4)-galactosyltransferase EspJ which is involved in the biosynthesis of exopolysaccharides in Lactobacillus delbrueckii; High confidence in function and specificity.
 
   0.681
CAZ96058.1
Glycosyltransferase, family GT4; Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm; Specificity unclear.
 
    0.680
CAZ97904.1
Glycosyltransferase, family GT4; Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm; Specificity unclear.
 
    0.656
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.