STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CAZ96082.1The generic name 'NUDIX hydrolases' corresponds to pyrophosphatases cleaving a NUcleoside DIphosphate linked to some other moiety X. These enzymes hydrolyze diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP). Localized in the cytoplasm; Specificity unclear. (225 aa)    
Predicted Functional Partners:
nadC
Quinolinic acid phosphoribosyl transferase (QPRTase or QAPRTase) or nicotinate-nucleotide pyrophosphorylase catalyses the conversion of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP), in the presence of Mg2+, to nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. This enzyme provides the de novo source of NAMN for NAD biosynthesis; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the NadC/ModD family.
 
  
 0.667
araD
L-ribulose-5-phosphate 4-epimerase catalyzes the conversion of L-ribulose 5-phosphate into D-xylulose 5-phosphate. This is the third step of the L-arabinose catabolism. AraD belongs to the class II aldolase family. Binds one zinc ion by subunit. Localized in the cytoplasm; High confidence in function and specificity.
  
    0.590
araB
Ribulokinase catalyzes the phosphorylation of ribulose. This is the second step of the arabinose catabolism. AraB belongs to the FGGY family of the carbohydrate kinases; High confidence in function and specificity.
       0.575
sglT
Sodium/glucose symporter SglT; Actively transports glucose into cells by Na(+) cotransport. Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient is used to drive solute accumulation against a concentration gradient. Features fourteen transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
    0.528
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
  
    0.504
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.481
nadR
Nicotinamide-nucleotide adenylyltransferase / Ribosylnicotinamide kinase; Bifunctional enzyme involved in the nicotinate and nicotinamide metabolism possessing both NMN (nicotinamide mononucleotide) adenylytransferase (NMNAT) and Ribosylnicotinamide kinase (RNK) activities. NMNAT is an indispensable activity in the biosynthesis of NAD(+) and NADP(+) synthesizing NAD via the salvage pathway. RNK converts the N-ribosylnicotinamide to nicotinamide ribonucleotide; Localized in the cytoplasm. However, this bifunctional enzyme would loosely associate with the membrane through its interaction [...]
 
   
 0.481
CAZ96078.1
FAD-dependent amine oxidoreductase; The main role of amine oxidases is to provide a source of ammonium; Adopts a Rossmann fold; Uses FAD as prosthetic group; Localized in the cytoplasm; Specificity unclear.
 
    0.451
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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