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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94075.1Methyltransferases; Enzyme that uses S-AdoMet in the methylation of diverse substrates; Belongs to the UPF0011 family; Localized in the cytoplasm; Specificity unclear. (241 aa)    
Predicted Functional Partners:
ptpA
The low molecular weight (LMW) protein-tyrosine phosphatases (or acid phosphatases) catalyse the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzyme intermediate; Belongs to the Tyrosine-specific protein phosphatases family; Localized in the cytoplasm; High confidence in function and specificity.
     0.930
dnaA
Chromosomal replication initiator protein, DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
    0.928
CAZ96331.1
Adenine-specific DNA methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
  
  
 0.542
CAZ94076.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.467
prmA
PrmA methylates ribosomal protein L11. Uses S-adenosylmethionine as cofactor. Localized in the cytoplasm; High confidence in function and specificity.
 
  
 0.421
CAZ97816.1
tRNA/rRNA methyltransferase; Catalyzes the site-specific methylation of the 2' hydroxy group of the ribose in rRNA or tRNA, using the S-AdoMet; Contains a N-terminal RNA 2'-O ribose methyltransferase substrate binding domain and a C-terminal catalytic domain also involved in the dimer formation that adopts an alpha/beta knot fold; Belongs to the RNA methyltransferase TrmH family; Localized in the cytoplasm; Family membership.
 
   
 0.414
CAZ97824.1
Conserved hypothetical protein; Protein that consists of a WbqC-like domain functionally uncharacterised; Could belong to the WbqC-like protein family; Localized in the cytoplasm.
  
  
 0.407
CAZ94964.1
Endonuclease; Protein that consists of an GIY-YIG catalytic domain of unknown function found in the amino terminal region of excinuclease abc subunit c (region 1 of UvrC) and in few other nucleases from bacteria and bacteriophages; Localized in the cytoplasm; Function unclear.
  
  
 0.407
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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