STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94279.1Sulfatase, family S1-17; Modular protein consisting of a C-terminal domain of unknown function (DUF814) and a N-terminal domain belonging to the family 1 of sulfatases. The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Family membership. (600 aa)    
Predicted Functional Partners:
CAZ94278.1
Conserved hypothetical protein; Contains a C-terminal domain of unknown function (100 aa) and a lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Belongs to the glycosyl hydrolase 43 family.
 
     0.800
CAZ94280.1
Conserved hypothetical membrane protein; Contains one N-terminal transmembrane segment, then four N-terminal tetratricopeptide repeats (TPR), and a C-terminal LuxR-type HTH domain. The TPRs and the HTH domains are separated by a second transmembrane segment; This Protein could interact with the DNA (transcriptional control or transcription factor); localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
     0.565
fgeA
C-alpha-formylglycine-generating protein; Converts newly synthesized inactive sulfatases to their active form by modifying an active site cysteine or serine residue to 3-oxoalanine; Putatively localized in the outer membrane; Specificity unclear.
 
   0.488
CAZ97765.1
This enzyme belongs to the family 74 of the glycoside hydrolases. These proteins consist of a tandem repeat of two similar domains, which are both folded into seven-bladed beta-propeller structures. The conserved catalytic residues are Asp70 and Asp 549. Features a signal peptide cleaved between the residues 24 and 25; Specificity unclear.
  
     0.453
CAZ97735.1
Conserved hypothetical lipoprotein; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Conserved hypothetical protein.
  
     0.448
CAZ97762.1
Conserved hypothetical protein; This protein displays distant similarity with glycoside hydrolases of the family 74 (GH74). These proteins consist of a tandem repeat of two similar domains, which are both folded into seven-bladed beta- propeller structures. But the two conserved catalytic aspartatic residues are substituted here by two asparagine residues. Features a signal peptide cleaved between the residues 19 and 20.
  
     0.435
CAZ97761.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein.
 
     0.408
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.