STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lolALolA is a molecular chaperone that participates in the translocation of lipoproteins from the cytoplasmic membrane to the outer membrane. LolA forms a complex with lipoproteins that do not possess an aspartate residue after the N-terminal Cys residue; Contains a signal peptide cleaved between residues 17 and 18; Localized in the periplasmic space; High confidence in function and specificity. (205 aa)    
Predicted Functional Partners:
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II, also known as beta-ketoacyl synthase II, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. FabF Has a preference for short chain acid substrates; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
   
 0.954
fabZ1
(3R)-Hydroxymyristoyl-[acyl-carrier-protein] dehydratase (FabZ) catalyses the dehydratation of beta-hydroxyacyl-ACP generated by FabG to trans-2-enoyl-ACP. This is the third step of the fatty acid elongation cycle. FabZ forms a hexamer (a trimer of dimers) where the monomer adopts a beta + alpha \hotdog\ fold; Localized in the cytoplasm; High confidence in function and specificity.
 
   
 0.952
fabB3
3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
   
 0.923
CAZ96190.1
Exporter / acyltransferase; This protein encompasses a N-terminal conserved domain predicted to be an exporter containing 13 transmembrane helices (residues 1-809) and a C-terminal catalytic domain belonging to the phospholipid/glycerol acyltransferase family (810-1228); Localized in the cytoplasmic membrane; Function unclear.
 
    0.917
CAZ96193.1
Glycosyltransferase, family GT2; Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases., Features four transmembrane helices in C-terminus. Localized in the cytoplasmic membrane.,; Specificity unclear.
 
    0.915
CAZ96189.1
Flavin containing amine oxidoreductase which contains a N-terminal DAO (D-amino acid oxidase) domain and one tranmembrane segment; Use FAD as cofactor; Belongs to the carotenoid/retinoid oxidoreductase family; Localized in the cytoplasmic membrane; Function unclear.
 
     0.909
CAZ96213.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
   
 0.902
acpP2
Acyl carrier protein (ACP) is the carrier of the growing fatty acid chain in fatty acid biosynthesis. ACP is produced as an apoprotein and is converted to its active form by [ACP]synthase (AcpS); Localized in the cytoplasm; High confidence in function and specificity.
 
    0.898
fabB4
3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
   
 0.898
CAZ96185.1
Peptidase family C45 contains autolytic endopeptidases. The active site cysteine becomes the new N-terminus following the autolytic cleavage. Features a C-terminal TPR domain. Signal peptide of lipoprotein cleaved between the residues 21 and 22. Localized in the cytoplasmic membrane; Specificity unclear.
 
     0.888
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.