STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96238.1KGW repeats protein; This conserved hypothetical protein contains KGW repeats; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein. (375 aa)    
Predicted Functional Partners:
hutH
Histidine ammonia-lyase converts L-histidine to urocanate and ammonia. This is the first step of the histidine degradation pathway. The active site is 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly; Localized in the cytoplasm; High confidence in function and specificity.
 
  
 0.811
CAZ96226.1
Conserved hypothetical protein distantly related to (3R)-Hydroxymyristoyl-[acyl-carrier-protein] dehydratase (FabZ); Localized in the cytoplasm.
 
     0.794
darA
Dialkylrecorsinol condensing enzyme; DarA catalyzes the head-to-head condensation of two beta-ketoacyl thioester intermediates (fatty acid-derived precursors) forming a dioxocyclohexene intermediate; Contains a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
     0.770
CAZ96195.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 17 and 18; Localized in the periplasmic space; Conserved hypothetical protein.
 
     0.720
CAZ96219.1
ABC-2 type exporter, permease component; ABC-2 Type (ATP-binding cassette) transporter membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership.
 
  
 0.720
CAZ96224.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.678
acpP3
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
  
 0.678
CAZ96223.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.650
fabG2
3-oxoacyl-[acyl-carrier protein] reductase; FabG catalyzes the first reduction step of the fatty acid biosynthesis pathway. Belongs to the short- chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
 
     0.621
darB
DarB is homologous to 3-oxoacyl-[acyl-carrier-protein] synthase III, also known as beta-ketoacyl-ACP synthase III (FabH), which catalyses the first condensation step within the fatty acid synthesis pathway converting the Acyl-[acyl-carrier-protein] to 3-oxoacyl-[acyl-carrier-protein]; Localized in the cytoplasm; Specificity unclear.
 
     0.616
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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