STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aehAalpha-Amino acid ester hydrolases (AEHs) catalyze the hydrolysis and synthesis of esters and amides with an alpha-amino group. They can synthesize beta-lactam antibiotics from acyl compounds and beta-lactam nuclei obtained from the hydrolysis of natural antibiotics. Belongs to the family S15 of the peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 14 and 15; Localized in the outer membrane; Specificity unclear. (641 aa)    
Predicted Functional Partners:
CAZ96261.1
Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Contains a N-terminal domain of unknown function and a C-terminal Thiol-disulfide oxidoreductase domain; Belongs to the thioredoxin family; Signal peptide cleaved between residues 18 and 19; Localized in the periplasmic space; Specificity unclear.
       0.613
axeA
Acetyl xylan esterase, family CE7; Acetyl xylan esterase catalyzes the hydrolysis of acetyl groups of xylan; Contains a signal peptide cleaved between the residues 21 and 22; Belongs to the family 7 of carbohydrate esterases (CE7); Localized in the periplasmic space; High confidence in function and specificity.
       0.613
cda2
Cda is a calcium-dependent ATPase. Vanadate strongly inhibits its activity; Belongs to the alkaline phosphatase clan, type I phosphodiesterase family; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; High confidence in function and specificity.
 
     0.470
mfdA
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
     
 0.450
cda1
Cda is a calcium-dependent ATPase. Vanadate strongly inhibits its activity; Belongs to the alkaline phosphatase clan, type I phosphodiesterase family; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; High confidence in function and specificity.
 
     0.422
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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