STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96349.1Sulfatase, family S1-24 / gluconolactonase; Modular protein containing a N-terminal domain belonging to family 1 of sulfatases and a C-terminal gluconolactonase domain. The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates. Gluconolactonases hydrolyze the gluconolactone to gluconate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 24; Lipoprotein signal peptide cleaved between the residues 16 an [...] (757 aa)    
Predicted Functional Partners:
nanH
Sialidase, family GH33; Sialidase catalyzes the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. It belongs to the family 33 of the glycoside hydrolases. Features a signal peptide cleaved between residues 26 and 27. Localized in the periplasm; High confidence in function and specificity.
  
 
  0.914
sgsA2
The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Lipoprotein with a signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; High confidence in function and specificity.
 
   
0.841
CAZ96350.1
Sulfatase, family S1-20; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Putative lipoprotein signal peptide cleaved between the residues 27 and 28; Possibly localized in the outer membrane; Family membership.
 
   
0.725
CAZ95112.1
This conserved protein belongs to the (Trans)glycosidase superfamily, which is included in the TIM beta/alpha-barrel fold. This protein is distantly related to the glycoside hydrolases from the family GH36; Localized in the cytoplasm; Family membership.
    
  0.663
CAZ96247.1
This conserved protein belongs to the (Trans)glycosidase superfamily, which is included in the TIM beta/alpha-barrel fold. Distantly related to the glycoside hydrolases 36 (GH36); Localized in the cytoplasm; Family membership.
    
  0.663
CAZ97661.1
This enzyme is a modular protein consisting of a N-terminal module belonging to the family 6 of the carbohydrate esterases (CE6; 26-342), a central alpha-galactosidase domain belonging to family 27 of the glycoside hydrolases (GH27; 343-733) and a C-terminal domain of unknown function (734-866). Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. The catalytic machinery is a Ser-His-Asp triad. Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharide [...]
    
  0.663
CAZ98092.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein.
  
    0.588
CAZ96090.1
Conserved hypothetical protein; Contains a central transmembrane helix; Localized in the cytoplasmic membrane.
  
    0.453
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.