Alpha-galactosidase, family GH110; Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides. Belongs to the family 110 of the glycoside hydrolases. Likely adopts a right handed parallel beta-helix fold. Signal peptide cleaved between the residues 26 and 27. Localized in the periplasmic space; High confidence in function and specificity.

Sulfatase, family S1-20; Modular protein consisting of a N-terminal domain belonging to the family 1 of sulfatases and a C-terminal PA14 domain putatively involved in the protein or carbohydrate binding; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Localized [...]

The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Signal peptide putatively cleaved between the residues 25 and 26; Possibly localized in the periplasmic space; High confidence in function and specificity.

The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Lipoprotein with a signal peptide cleaved between the residues 26 and 27; Localized in the outer membrane; High confidence in function and specificity.

C-alpha-formylglycine-generating protein; Converts newly synthesized inactive sulfatases to their active form by modifying an active site cysteine or serine residue to 3-oxoalanine; Putatively localized in the outer membrane; Specificity unclear.

Iota-carrageenase, family GH82; The Iota-carrageenases hydrolyse the 1,4-beta-D-galactosidic linkages in the iota-carrgeenan giving the tetramer as the predominant product; Belongs to the family 82 of glycoside hydrolases (GH82); Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; High confidence in function and specificity.

SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Probably localized in the outer membrane; Family membership.

The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.

Sulfatase, family S1-15; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Signal peptide cleaved between the residues 21 and 22; Possibly localized in the periplasmic space; Family membership.