STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CAZ96354.1Sulfatase, family S1-20; Modular protein consisting of a N-terminal domain belonging to the family 1 of sulfatases and a C-terminal PA14 domain putatively involved in the protein or carbohydrate binding; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Localized [...] (708 aa)    
Predicted Functional Partners:
CAZ96353.1
Sulfatase, family S1-16; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Family membership.
 
   
0.816
sgsA3
The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Signal peptide putatively cleaved between the residues 25 and 26; Possibly localized in the periplasmic space; High confidence in function and specificity.
 
    
0.745
CAZ96356.1
Alpha-galactosidase, family GH110; Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides. Belongs to the family 110 of the glycoside hydrolases. Likely adopts a right handed parallel beta-helix fold. Signal peptide cleaved between the residues 19 and 20. Localized in the periplasmic space; High confidence in function and specificity.
 
     0.727
sgsA4
The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Lipoprotein with a signal peptide cleaved between the residues 26 and 27; Localized in the outer membrane; High confidence in function and specificity.
 
    
0.700
CAZ96355.1
Alpha-galactosidase, family GH110; Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides. Belongs to the family 110 of the glycoside hydrolases. Likely adopts a right handed parallel beta-helix fold. Signal peptide cleaved between the residues 26 and 27. Localized in the periplasmic space; High confidence in function and specificity.
       0.675
CAZ96361.1
Sulfatase, family S1-15; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Signal peptide cleaved between the residues 21 and 22; Possibly localized in the periplasmic space; Family membership.
 
    
0.424
CAZ96332.1
Xylose isomerase-like TIM barrel protein. Features a signal peptide cleaved between the residues 32 and 33. Localized in the periplasm; Conserved hypothetical protein.
  
     0.417
CAZ96371.1
Sulfatase, family S1-16; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Family membership.
 
   
0.406
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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