STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
sgsA5The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic membrane or/and outer membrane; High confidence in function and specificity. (525 aa)    
Predicted Functional Partners:
fucA11
Alpha-L-fucosidase, family GH29; The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 26 and 27; Localized in the periplasmic space; High confidence in function and specificity.
       0.746
CAZ96362.1
Hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the xylose isomerase-like TIM barrel family; Exported by the twin-arginine translocation pathway signal; High confidence in function and specificity.
       0.639
CAZ96363.1
Conserved hypothetical protein; Signal peptide putatively cleaved between the residues 19 and 20; Localized in tyhe periplasmic space.
       0.639
CAZ96364.1
FAD-dependent oxidoreductase; Belongs to the GMC oxidoreductase family; Localized in the cytoplasm; Specificity unclear.
       0.639
CAZ96370.1
Sulfatase, family S1-20; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Family membership.
 
    
0.625
CAZ96371.1
Sulfatase, family S1-16; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Family membership.
 
    
0.615
sgsA6
The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Localized in the cytoplasm; High confidence in function and specificity.
 
    
0.609
CAZ97767.1
Sulfatase, family S1-30; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 30; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Family membership.
  
     0.604
CAZ96361.1
Sulfatase, family S1-15; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Signal peptide cleaved between the residues 21 and 22; Possibly localized in the periplasmic space; Family membership.
 
    
0.561
CAZ96367.1
Glycoside hydrolase that belongs to the family 36 of glycoside hydrolases (GH36); Exported in the periplasmic space by twin-arginine translocation pathway signal; Family membership.
       0.520
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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