STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96382.1Conserved hypothetical protein distantly related to the glycoside hydrolases of the families GH37 and GH63 (clan GH-G); Localized in the cytoplasm. (436 aa)    
Predicted Functional Partners:
CAZ96381.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-99) and the Plug module (116-229) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership.
 
     0.893
otsAB
Trehalose-6-phosphate synthase/phosphatase, family GT20; This enzyme is involved in the biosynthesis of trehalose. It is a fusion protein between the trehalose-6-phosphate synthase (OtsA) and the trehalose-6-phosphate phosphatase (OtsB). Trehalose-6-phosphate synthase catalyzes the reaction: UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate. It belongs to the family 20 of the glycosyltransferases (GT20). trehalose-6-phosphate phosphatase catalyzes the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate. Localized in the cytoplasm; High confidence i [...]
  
 
 0.775
katA2
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.748
nisA
Sodium/iodide symporter; Transporter that mediates iodide uptake. Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes. Thereby the energy stored in an inwardly directed electrochemical sodium gradient is used to drive solute accumulation against a concentration gradient; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
   
 0.726
katA1
Catalase; This enzyme is a mono-functional haem-containing catalase that acts as an antioxidant enzyme catalyzing the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects. Localized in the cytoplasm; High confidence in function and specificity.
   
  
 0.614
CAZ96380.1
The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Specificity unclear.
 
     0.597
glxK
Glycerate kinase; Enzyme involved in glycine, serine and threonine metabolism, Glycerolipid metabolism and Glyoxylate and dicarboxylate metabolism; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the glycerate kinase type-1 family.
 
     0.491
CAZ94097.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (27-112) and the Plug module (129-240) acting as a channel gate; The signal peptide is cleaved between the residues 22 and 23; Family membership.
  
     0.478
CAZ94166.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.455
CAZ94611.1
Conserved hypothetical membrane protein; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.442
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: medium (42%) [HD]