STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AsnSAsparaginyltRNA synthetase catalyse the attachment of the aminoacid asparagine to the 3'-hydroxyl of the tRNA. It is an homodimer; Belongs to the class-II aminoacyl-tRNA synthetase family; Localized in the cytoplasm; High confidence in function and specificity. (477 aa)    
Predicted Functional Partners:
metG
Methionyl-tRNA synthetase, class Ia; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.914
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 0.880
proS
Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 0.864
argS
Arginyl-tRNA synthetase also called Arginine-tRNA ligase is a monomeric enzyme that catalyzes the transfer of arginine to specific tRNA molecule as the first step in protein biosynthesis; Belongs to the class-I aminoacyl-tRNA synthetase family; Localized in the cytoplasm; High confidence in function and specificity.
 
 0.801
leuS
Leucyl-tRNA synthetase catalyses the attachment of leucine to its cognate transfer RNA molecule in a highly specific two-step reaction. Belongs to the class I of the aminoacyl-tRNA synthetases. It is a monomer and adopts a Rossmann fold. Localized in the cytoplasm; High confidence in function and specificity.
 
 0.792
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.774
glyQS
Glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.738
pheT
Phenylalanyl-tRNA synthetase catalyzes the attachment of phenylalanyl to its cognate transfer RNA molecule in a highly specific two-step reaction. It is an alpha2/beta2 tetramer composed of 2 subunits that belongs to class II aminoacyl-tRNA synthetases. PheT codes the beta subunit and folds as an anti-parallel beta-sheet flanked by alpha-helices. Phenylalanyl-tRNA synthetase binds 2 magnesium ions per tetramer. Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.716
rpoN
RNA polymerase sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. sigma-54 factors consist of three distinct regions: A conserved N-terminal glutamine-rich region (50 aa) that contains a potential leucine zipper motif. A region which is not conserved. A conserved C-terminal region (350 aa) that contains a second potential leucine zipper, a potential DNA-binding 'helix-turn-helix' motif and a perfectly conserved octapeptide whose function is not known; Localized in the cytoplasm; High confidenc [...]
       0.705
CAZ96491.1
Hypothetical membrane protein; Contains seven transmembrane segments; Localized in the cytoplasmic membrane; Hypothetical protein.
     
 0.663
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.