STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cutCCopper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (240 aa)    
Predicted Functional Partners:
aspG
Glycosylasparaginases 2; Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins; Protein exported in the periplasmic space; Protein contains a Twin-arginine translocation pathway signal that does not use the standard general secretory (Sec) pathway; Heterodimer of an alpha and a beta chain; High confidence in function and specificity.
 
     0.827
nahA1
Beta-N-acetylhexosaminidase, family GH20; Beta-N-acetylhexosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. Belongs to the family 20 of the glycoside hydrolases. Carbonyl oxygen of the C-2 acetamido group of the substrate acts as the catalytic nucleophile/base in the family GH20. They are involved in different pathways such as the N-Glycan degradation, aminosugars metabolism, glycosaminoglycan degradation and globoside metabolism. Signal peptide cleaved between the residues 23 and 24. Localized in the periplas [...]
 
     0.669
CAZ96506.1
Metallophosphoesterase; Protein that catalyzes the hydrolysis of any phospho ester bond; Contains four transmembrane segments; Binds 2 divalent metal cations; Belongs to the metallophosphoesterase superfamily; Localized in the cytoplasmic membrane; Specificity unclear.
       0.632
nagB2
Bifunctional enzyme with a N-terminal glucosamine-6-phosphate (GlcN6P) deaminase domain and a C-terminal deacetylase domain. GlcN6P deaminase catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate to form fructose 6-phosphate and ammonium ion in the N-acetylglucosamine utilization pathway. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. The C-terminal domain belongs to the PIG-L family, which includes various deacetylases, such as the mammalian and yeast N-acetylglucosaminylphosphatidylinositol de-N-acetylase and the diacetylchitobiose deac [...]
 
   
 0.629
nahA3
Beta-N-acetylhexosaminidase, family GH20; Beta-N-acetylhexosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. Carbonyl oxygen of the C-2 acetamido group of the substrate acts as the catalytic nucleophile/base; Belongs to the family 20 of the glycoside hydrolases (GH20); Signal peptide cleaved between residues 22 and 23; Localized in the periplasmic space; High confidence in function and specificity.
 
     0.610
nahA2
Beta-N-acetylhexosaminidase, family GH20; Beta-N-acetylhexosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; Belongs to the family 20 of the glycoside hydrolases (GH20); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; High confidence in function and specificity.
 
     0.607
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
    0.554
nagB1
Glucosamine-6-phosphate deaminase or Glucosamine-6-phosphate isomerase catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion in the N-acetylglucosamine (GlcNAC) utilization pathway; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family; Localized in the cytoplasm; High confidence in function and specificity.
 
   
 0.529
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.519
trxA-2
Thioredoxin like protein; Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond; In this protein, the catalytic cysteins are replaced by an asparagine and by a serine; Family membership.
       0.441
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.