STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaCThe Sodium/hydrogen exchanger regulates the cytoplasmic pH, extruding the H+ generated during metabolism. It is involved also in the regulation of cell volume and in salt tolerance, due to Na+ uptake; Contains 13 transmembrane segmemts and a large cytoplasmic region at the carboxyl terminus; Belongs to the Na(+)/H(+) exchanger family; Integral cytoplasmic membrane protein; Family membership. (455 aa)    
Predicted Functional Partners:
CAZ94707.1
Conserved protein containing two N-terminal Calx-beta motifs separated by a CUB domain and followed by a C-terminal beta helix fold domain of unknown function. Calx-beta motifs are involved in calcium-binding. CUB domains contain four conserved cysteines which probably form two disulfide bridges. The structure of the CUB domain has been predicted to be a beta-barrel; Conserved hypothetical protein.
  
     0.755
CAZ95257.1
Conserved hypothetical membrane protein; Contains a putative lipoprotein signal peptide cleaved between the residues 15 and 16; Possibly localized in the outer membrane; Conserved hypothetical protein.
  
     0.725
CAZ95454.1
Conserved hypothetical protein; Localized in the cytoplasm.
  
     0.592
CAZ95786.1
Conserved hypothetical membrane protein; Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.591
CAZ95455.1
Hypothetical protein. Putatively localized in the cytoplasm.
  
     0.552
CAZ96814.1
Beta-helix fold protein; This protein likely adopts a right handed parallel beta-helix fold. Displays also a C-terminal PKD domain; Signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Function unclear.
  
     0.536
rimP
Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.517
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
       0.499
CAZ98770.1
Protein belonging to the OmpA family. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Family membership.
  
   
 0.499
CAZ96813.1
CBM6 containing protein; Conserved protein featuring a N-terminal conserved domain of unknown function, a central PKD domain and a C-terminal carbohydrate binding module of the family 6. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm; Conserved hypothetical protein.
  
     0.495
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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