STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cgkAKappa-carrageenase, family GH16; Kappa-carrageenase Hydrolyses the 1,4-beta-D-galactosidic linkages in kappa-carrageenan giving the tetramer as the predominant product; Modular enzyme containing a N-terminal catalytic domain belonging to the family 16 of the glycoside hydrolases, a central Carbohydrate Binding Module of the family CBM16 and a C-terminal domain of unknown function; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space and possibly secreted in the outside medium; High confidence in function and specificity. (546 aa)    
Predicted Functional Partners:
porA
Beta-porphyranase A, family GH16; Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6- sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6- sulfate-(1->3)-beta-D-galactose. Some longer oligosaccharides of even number of residues are also observed. Inactive on the non-sulfated agarose portion of the porphyran backbone. Displays a strict requirement for C6-sulfate in the -2 and +1-binding subsites.
  
   
 0.774
CAZ96463.1
Conserved hypothetical protein; Shows a weak similarity with the glycoside hydrolases of the family 42 (GH42); Seems to be a lipoprotein with a signal peptide cleaved between residues 15 and 16; Putatively localised in the outer membrane.
  
     0.762
porE
Beta-porphyranase E, family GH16; Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6- sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6- sulfate-(1->3)-beta-D-galactose.
  
     0.745
CAZ94410.1
Modular protein containing a N-terminal domain adopting a parallel beta-helix fold and a C-terminal carbohydrate binding module of the family 16 (CBM16). The N-terminal domain is distantly related to the polysaccharide lyases of the family 9 (PL9). Features a signal peptide cleaved between residues 29 and 30. Localized in the periplasm; Specificity unclear.
  
     0.744
CAZ98461.1
Beta-helix fold protein; Conserved protein adopting a parallel beta-helix fold. Features a signal peptide cleaved between the residues 27 and 28. Localized in the periplasm; Conserved hypothetical protein.
  
     0.739
CAZ96570.1
Protein that contains in the N-terminal part, one cadherin like domain and in its C-terminal part, five PKD repeats. The PKD domains are present in the extracellular parts of proteins involved in interactions with other proteins or polysaccharides; Signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane.
  
     0.732
agaA
Beta-agarase A, family GH16; Cleaves the beta-1,4-linkages between beta-D-galactose and alpha-L-3,6-anhydro-galactose residues in agarose. Cleaves agarose in a random manner with retention of the anomeric-bond configuration, producing beta-anomers that give rise progressively to alpha-anomers when mutarotation takes place.
  
   
 0.728
cgiA2
Iota-carrageenase, family GH82; The Iota-carrageenases hydrolyse the 1,4-beta-D-galactosidic linkages in the iota-carrgeenan giving the tetramer as the predominant product; Belongs to the family 82 of glycoside hydrolases (GH82); Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; High confidence in function and specificity.
  
   
 0.722
porB
Beta-porphyranase B, family GH16; Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6- sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6- sulfate-(1->3)-beta-D-galactose. Some longer oligosaccharides of even number of residues are also observed. Inactive on the non-sulfated agarose portion of the porphyran backbone. In contrast to PorA, tolerates the presence of 3-6-anhydro-L-galactose in subsite -2.
  
   
 0.714
CAZ94916.1
Polysaccharide lyase, family PL9; This protein is modular with a N-terminal domain belonging to the family 9 of the polysaccharide lyases (23-622) and a C-terminal conserved domain of unknown function (661-915). The PL9 domain adopts a right handed parallel beta-helix fold. In contrast to other proteins from the PL9 family, a conserved domain of unknown function is inserted within loops of the beta-helix core (97-271). Such domain insertion in a beta-helix has been observed in the family GH82. Features a signal peptide cleaved between residues 23 and 24. Localized in the periplasm; Spe [...]
  
     0.710
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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