STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabDMalonyl CoA-acyl carrier protein transacylase is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein; High confidence in function and specificity. (295 aa)    
Predicted Functional Partners:
fabB2
3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.999
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
 
0.999
fabB6
3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.999
fabB5
3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 0.998
fabB3
3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 0.997
fabH2
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.991
fabH1
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.989
fabB4
3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.987
accD
Acetyl-coenzyme A carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
 
 
 0.987
fabB1
3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.986
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.