STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96604.1CBS domain protein; Contains a N-terminal CBS (cystathionine-beta-synthase) pair domain that can act as binding domains for adenosine derivatives such as AMP, ATP and S-AdoMet CBS domains are found attached to a wide range of other protein domains suggesting that CBS domains may play a regulatory role making proteins sensitive to adenosyl carrying ligands; Localized in the cytoplasm; Function unclear. (218 aa)    
Predicted Functional Partners:
CAZ96606.1
Conserved hypothetical protein; Signal peptide possibly cleaved between the residues 18 and 19; Putatively localized in the outer membrane.
 
     0.847
CAZ95666.1
Conserved protein belonging to the family DUF177; Localized in the cytoplasm; Family membership.
  
     0.715
gldJ
Lipoprotein involved in the gliding motility that contains an unknown function domain found in some eukaryotic and prokaryotic protein and in eukaryotic proteins required for post-translational modification of sulfatase; Signal peptide cleaved between the residues 23 and 24; Putatively localized in the outer membrane; Function unclear.
  
     0.693
gldD
Lipoprotein involved in the gliding motility; Signal peptide cleaved between the residues 17 and 18; localized in the cytoplasmic membrane; Function unclear.
 
     0.692
CAZ98751.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.687
gldB
Lipoprotein involved in the gliding motility; It is possible that GldB interacts with, or is involved in production of polysaccharides or glycoproteins; Signal peptide cleaved between the residues 16 and 17; Putatively localized in the cytoplasmic membrane; Function unclear.
  
     0.677
CAZ95840.1
Conserved hypothetical membrane protein; Contains a putative lipoprotein signal peptide cleaved between the residues 22 and 23; Possibly localized in the outer membrane; Conserved hypothetical protein.
  
     0.668
CAZ95527.1
Conserved hypothetical protein; Localized in the cytoplasm.
  
     0.652
CAZ96602.1
The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear.
 
    0.641
sprE
The SprE protein could be involved in the gliding motility; Contains four tetratrico peptide repeats (TPRs). TPRs mediate proteinprotein interactions. TPR adopts a helixturnhelix arrangement, with adjacent TPR motifs packing in a parallel fashion, resulting in a spiral of repeating anti-parallel alpha-helices. SprE contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Function unclear.
 
     0.637
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.