STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radCRadC plays a role in repair of DNA damage after UV and X-ray irradiation in prokaryotes; RadC may function specifically in recombinational repair that is associated with the replication fork. Involved in DNA repair; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the UPF0758 family. (232 aa)    
Predicted Functional Partners:
CAZ98118.1
Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.777
mreC
MreC (murein formation C) is involved in the rod shape determination and more generally in cell shape determination of bacteria whether or not they are rod-shaped; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
  
 0.762
CAZ95478.1
Phosphoribosyltransferase carries out phosphoryl transfer reactions on 5-phosphoribosyl-alpha1-pyrophosphate, an activated form of ribose-5-phosphate. Its exact specificity is still unknown; Localized in the cytoplasm; Function unclear.
 
    0.756
mutS1
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.732
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.701
CAZ96639.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.660
CAZ96640.1
5'-nucleotidase; Nucleotidase that shows high phosphatase activity toward three nucleoside 5'-monophosphates, UMP, dUMP, and dTMP, and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6-phosphogluconate. Is strictly specific to substrates with 5'-phosphates and shows no activity against nucleoside 2'- or 3'-monophosphates. Might be involved in the pyrimidine nucleotide substrate cycles; Uses Divalent metal cation as cofactors. Highest activity with manganese followed by magnesium and cobalt; Belongs to the HAD-like hydrolase superfamily; Localized in the cytoplasm; Hi [...]
       0.659
dprA
The protein Smf (or DprA) would be a new member of the recombination-mediator protein family, dedicated to natural bacterial transformation; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.582
CAZ96642.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein.
       0.561
mplA
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase is an enzyme involved in the biosynthesis of peptidoglycan which reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramic acid; Belongs to the MurCDEF family; Localized in the cytoplasm; High confidence in function and specificity.
       0.535
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.