STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94329.1This protein belongs to the family 105 of the glycoside hydrolases. These enzymes are involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. Asp183 is the putative catalytic residue (identical to Asp143 of the unsaturated rhamnogalacturonyl hydrolase from Bacillus subtilis, Itoh et al., 2006, BBRC 347, 10211029); Specificity unclear. (400 aa)    
Predicted Functional Partners:
kduI2
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.903
kduI3
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.650
kduI1
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.647
kduI4
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.646
CAZ97769.1
Polygalacturonase, family GH28; The polygalacturonases catalyze the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans; The tertiary structures show a stack of parallel beta strands that are coiled into a large helix; Belongs to the family 28 of glycoside hydrolases (GH28); Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; Specificity unclear.
     0.531
xylB
Beta-xylosidase, family GH43; Enzyme that hydrolyzes the beta-1,4-D-xylans linkage, to remove successive D-xylose residues from the non-reducing termini; Belongs to the family 43 of the glycoside hydrolase (GH43); Protein localized in the cytoplasm; High confidence in function and specificity.
 
     0.460
CAZ94327.1
Hypothetical periplasmic protein; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Hypothetical protein.
       0.460
CAZ97770.1
Polygalacturonase, family GH28; The polygalacturonases catalyze the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans; The tertiary structures show a stack of parallel beta strands that are coiled into a large helix; Belongs to the family 28 of glycoside hydrolases (GH28); Signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane and possibly secreted; Specificity unclear.
     0.433
pelA2
Pectate lyase, family PL1; Modular protein with a N-terminal TolA-like domain and a C-terminal pectate lyase domain. Pectate lyase catalyzes the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. The catalytic domain belongs to the family 1 of the polysaccharide lyases (PL1). Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
   
 0.424
CAZ95326.1
Conserved protein belonging to the DUF1593 family; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space and possibly secreted; Family membership.
 
  
 0.422
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (38%) [HD]