STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96762.1Manganese/fer transporter; Protein that Belongs to the NRAMP family (resistance-associated macrophage protein); This family of membrane proteins are divalent cation transporters; Contains 10 transmembrane segments; Possible peptide signal cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Family membership. (422 aa)    
Predicted Functional Partners:
alyA5
Alginate lyase, family PL7; Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends; Belongs to the family 7 of the polysaccharide lyases (PL7); Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; High confidence in function and specificity.
 
     0.745
pfp
Diphosphate-fructose-6-phosphate 1-phosphotransferase catalyzes the reversible phosphorylation of fructose-6-phosphate using pyrophoshate instead of ATP for phosphofructokinase (Pfk). Involved in glycolysis. It forms a homotetramer. Localized in the cytoplasm; High confidence in function and specificity.
       0.603
kdgK1
2-dehydro-3-deoxygluconokinase; The 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP) in the Entner-Doudoroff pathway. KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources; Belongs to the Carbohydrate kinase, PfkB family, 2-dehydro-3-deoxygluconokinase (KdgK) subfamily; Localized in the cytoplasm; High confidence in function and specificity.
       0.571
CAZ96765.1
Acetoin(diacetyl) reductase; The enzymes of this family are very similar and display high sequence identities, the substrate specificity is difficult to determine; A match to Glucose/ribitol dehydrogenase subfamily indicates that the protein is not an alcohol dehydrogenase, but another type of dehydrogenase or reductase; Possible signal peptide cleaved between the residues 20 and 21; Putatively localized in the periplasmic space; Family membership.
 
    0.564
CAZ96766.1
The Sugar permeases belong to the major facilitator superfamily (MFS) transporters that are single-polypeptide secondary carriers capable only of transporting small solutes (probably sugars in this case) in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Family membership.
 
     0.536
ybgK
Conserved hypothetical protein; Protein that shows some similarities with the uncharacterized YbgK protein from Escherichia coli K12. YbgK and YbgJ Probably are involved in a common metabolism; Contains a Allophanate hydrolase subunit 2 domain; Localized in the cytoplasm.
 
  
 0.467
CAZ96761.1
Conserved hypothetical protein belonging to the DUF1328 family. Contains two transmembrane helices; Localized in the cytoplasmic membrane; Family membership.
       0.465
CAZ98709.1
LamB family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
  
 0.427
CAZ96702.1
Conserved membrane lipoprotein; Lipoprotein with a signal peptide cleaved between the residues 25 and 26; Localized in the outer memebrane; Conserved hypothetical protein.
  
     0.419
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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