STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96770.1SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership. (476 aa)    
Predicted Functional Partners:
alyA2
Alginate lyase, family PL7; Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. It belongs to the family 7 of the polysaccharide lyases. Features a signal peptide cleaved between residues 32 and 33. Localized in the periplasm; High confidence in function and specificity.
 
   0.931
CAZ96771.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (26-98) and the Plug module (115-224) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership.
 
 
   0.927
CAZ96769.1
Conserved hypothetical lipoprotein; Contains a N-terminal PKD domain present in the extracellular parts of proteins involved in interactions with other protein or polysaccharides and a C-terminal putative carbohydrate binding module (CBM); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 28 and 29; Localized in the outer membrane; Conserved hypothetical protein.
 
     0.923
CAZ96767.1
Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; Contains an N-terminal HTH domain of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA and a C-terminal FCD domain that probably binds to a range of effector molecules that regulate the transcription of genes through the action of the N- terminal DNA-binding domain (HTH domain); Localized in the cytoplasm; Family membership.
 
     0.777
CAZ96766.1
The Sugar permeases belong to the major facilitator superfamily (MFS) transporters that are single-polypeptide secondary carriers capable only of transporting small solutes (probably sugars in this case) in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Family membership.
 
     0.705
CAZ96765.1
Acetoin(diacetyl) reductase; The enzymes of this family are very similar and display high sequence identities, the substrate specificity is difficult to determine; A match to Glucose/ribitol dehydrogenase subfamily indicates that the protein is not an alcohol dehydrogenase, but another type of dehydrogenase or reductase; Possible signal peptide cleaved between the residues 20 and 21; Putatively localized in the periplasmic space; Family membership.
 
     0.660
CAZ94166.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.639
CAZ97719.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (58-131) and the Plug module (147-263) acting as a channel gate; The signal peptide is cleaved between the residues 38 and 39; Family membership.
 
 
   0.620
alyA3
Alginate lyase, family PL17; Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. It belongs to the family 17 of the polysaccharide lyases. Features an uncleaved signal peptide. Features a signal peptide cleaved between residues 25 and 26. Localized in the periplasm; High confidence in function and specificity.
  
     0.615
CAZ94386.1
TonB-dependent Transducer; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (85-159), and a Plug module (175-281) acting as the channel gate; The signal peptide is cleaved between the residue 32 and 33; Family membership.
 
 
   0.582
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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