STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96811.1The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership. (270 aa)    
Predicted Functional Partners:
wrbA
NAD(P)H dehydrogenase [quinone]; The enzyme catalyse the NAD(P)H-dependent two-electron reductions of quinones; It apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons to protect cells against damage by free radicals and reactive oxygen species; It has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone; Uses a FAD cofactor; Localized in the cytoplasm; High confidence in function and specificity.
 
     0.866
CAZ96812.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.752
CAZ96305.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Putatively localized in the outer membrane; Family membership.
  
     0.654
CAZ97150.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Probably localized in the outer membrane; Family membership.
  
     0.597
CAZ98697.1
The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership.
  
     0.505
CAZ98698.1
The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership.
  
     0.486
CAZ96306.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-98) and the Plug module (117-220) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership.
  
     0.483
CAZ97151.1
TonB-dependent Transducer; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a N-terminal carboxypeptidase regulatory domain (117-190), a Plug module (206-316) acting as the channel gate; The signal peptide is cleaved between the residue 22 and 23; Family membership.
  
     0.479
CAZ96817.1
Conserved hypothetical membrane protein; Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.416
CAZ96819.1
Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership.
  
     0.415
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.