STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96821.1The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership. (387 aa)    
Predicted Functional Partners:
gltA-2
Glutamate synthase [NADPH] large chain; Glutamate synthase is a key enzyme in the early stages of the assimilation of ammonia. It is a complex iron-sulfur flavoprotein catalyzing the reductive transfer of the amido nitrogen from L-glutamine to 2-oxoglutarate to form two molecules of L-glutamate via intramolecular channelling of ammonia from the amidotransferase domain to the FMN-binding domain. Glutamate synthase forms an aggregate of 4 catalytic active heterodimers, consisting of a large and a small subunit (GltB). GltA binds as cofactors a 3Fe-4S cluster, a FAD and a FMN. Localized i [...]
   
 
 0.609
CAZ96025.1
Transposase, family 12; The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 12 of transposases; Localized in the cytoplasm; Family membership.
  
     0.553
CAZ98141.1
Transposase, family 12; The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 12 of transposases family; Localized in the cytoplasm; Family membership.
  
     0.553
CAZ96934.1
Transposase, family 12; The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 12 of transposases; Localized in the cytoplasm; Family membership.
  
     0.552
CAZ95047.1
Transposase, family 12; The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 12 of transposase; Localized in the cytoplasm; Family membership.
  
     0.551
rpoA
DNA-dependent RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.548
CAZ97683.1
The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership.
 
 
 0.523
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
  
 
 0.497
CAZ94435.1
The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership.
 
 
 0.496
CAZ97601.1
The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership.
 
 
 0.493
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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