STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysSCysteinyl-tRNA synthetase catalyzes the attachment of cysteine to its cognate transfer RNA molecule in a highly specific two-step reaction. It is a monomer and belongs to the class I of the aminoacyl-tRNA synthetases. It binds one zinc ion as cofactor. Localized in the cytoplasm; High confidence in function and specificity. (492 aa)    
Predicted Functional Partners:
cysE
Serine O-acetyltransferase is involved in L-cyteine biosynthesis. It catalyzes the reaction: Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine. Localized in the cytoplasm; High confidence in function and specificity.
 
  
 0.984
cysM
The cysteine synthase is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid. Uses the pyridoxal phosphate as cofactor (vitamin B6) attached to a conserved lysine residue. Belongs to the cysteine synthase/cystathionine beta-synthase family; Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.917
CAZ95328.1
Glycoside hydrolase, family GH114; Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety. Belongs to the family 114 of the glycoside hydrolases. Family GH114 contains endo-alpha-1,4-polygalactosaminidases, but the specificity of this protein is unclear. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 29 and 30. Localized in the outer membrane; Specificity unclear.
     
 0.911
cysK2
The cysteine synthase is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid; Uses the pyridoxal phosphate as cofactor (vitamin B6) attached to a conserved lysine residue; Belongs to the cysteine synthase/cystathionine beta-synthase family; Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.861
cysK1
The cysteine synthase is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid; Uses the pyridoxal phosphate as cofactor (vitamin B6) attached to a conserved lysine residue; Belongs to the cysteine synthase/cystathionine beta-synthase family; Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.803
folE1
GTP cyclohydrolase I catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate. FolE is a homodecamer, composed of a dimer of pentamers. It is an allosteric enzyme, whose activity is modulated by K(+), divalent cations, UTP, and tetrahydrobiopterin. Tetrahydrobiopterin is an inhibitor of this enzyme. Localized in the cytoplasm; High confidence in function and specificity.
     
 0.779
argS
Arginyl-tRNA synthetase also called Arginine-tRNA ligase is a monomeric enzyme that catalyzes the transfer of arginine to specific tRNA molecule as the first step in protein biosynthesis; Belongs to the class-I aminoacyl-tRNA synthetase family; Localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.769
metG
Methionyl-tRNA synthetase, class Ia; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
  
 0.759
leuS
Leucyl-tRNA synthetase catalyses the attachment of leucine to its cognate transfer RNA molecule in a highly specific two-step reaction. Belongs to the class I of the aminoacyl-tRNA synthetases. It is a monomer and adopts a Rossmann fold. Localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.749
thrS
Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
 
  
 0.746
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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