STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ96942.1Rieske [2Fe-2S] iron-sulfur protein; Protein that contains an unknown function N-terminal domain and a C-terminal Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines that one Fe ion while the other Fe ion is coordinated by two conserved histidines; Prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Function unclear. (149 aa)    
Predicted Functional Partners:
ccoNO
Fusion of the subunits CcoN and CcoO of the Cytochrome cbb3 oxidase. Converts the ferrocytochrome to ferricytochrome. Belongs to the ccoNOQP operon. Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
 
 0.984
fdx
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. It binds two 4Fe-4S clusters; Localized in the cytoplasm; Function unclear.
  
 
 0.983
CAZ95417.1
Peptidase family M16 contains metalloendopeptidases. Two of the zinc ligands occur in the motif His-Xaa-Xaa-Glu-His. The glutamate in this HXXEH motif is important for catalysis, and a glutamate more C- terminal is the third zinc ligand. Features a signal peptide cleaved between the residues 20 and 21. Localized in the periplasm; Specificity unclear.
   
 0.980
CAZ95418.1
This protein belongs to the family 16 of the metallopeptidase, but the catalytic motif His-Xaa-Xaa-Glu-His (zinc-binding) is missing. This protein also displays a conserved C-terminal domain of unknown function. Features a signal peptide cleaved between the residues 19 and 20. Localized in the periplasm; Function unclear.
   
 0.980
coxN
Cytochrome c oxidase is an oligomeric enzymatic complex which is a component of the respiratory chain and is involved in the transfer of electrons from cytochrome c to oxygen catalyzing the reduction of oxygen to water; Subunit I (CO I) is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred, via the copper A center of subunit II and a low-spin heme (heme a) of subunit 1, to the CuB-heme a3 (or heme o) bimetallic center of subunit 1; contains 12 transmembrane segmemts; Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
 
 0.974
coxC/ctaE
Associates with subunits I, II and IV to form cytochrome c oxidase the terminal enzyme of the respiratory chain; The functional role of subunit III is not yet understood; Contains five transmembrane segmemts; Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
 
 0.963
cyoC
Cytochrome O ubiquinol oxidase, subunit III; Cytochrome O terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration; Heterooctamer of two A chains, two B chains, two C chains and two D chains; Contains five transmembrane segmemts; Localized in the cytoplasmic membrane; Family membership.
  
 
 0.963
coxM
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.958
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
   
 
 0.911
sdhB
Succinate dehydrogenase is a complex containing three subunits: a flavoprotein, an iron-sulfur protein and cytochrome b-558. It is involved in the citrate cycle and catalyzes the reaction: succinate + acceptor = fumarate + reduced acceptor. It uses a FAD as a cofactor. SdhB is the iron-sulfur subunit. Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.880
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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