STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
priAPrimosomal protein N' (replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (817 aa)    
Predicted Functional Partners:
ssb1
Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
 
 
 0.892
ssb2
Single-stranded DNA-binding protein (SSB) is essential for replication of the chromosome. It is also involved in DNA recombination and repair. This protein forms a homotetramer. Localized in the cytoplasm; High confidence in function and specificity.
 
 
 
 0.864
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    0.835
rbnA
The ribonuclease BN is a 3' to 5' exoribonuclease necessary for 3' maturation of some tRNA molecules; The substrate specificity of RNase BN appears to be very narrow and its biological role is uncertain. Contains six transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
     0.826
nadC
Quinolinic acid phosphoribosyl transferase (QPRTase or QAPRTase) or nicotinate-nucleotide pyrophosphorylase catalyses the conversion of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP), in the presence of Mg2+, to nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. This enzyme provides the de novo source of NAMN for NAD biosynthesis; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the NadC/ModD family.
       0.771
pheT
Phenylalanyl-tRNA synthetase catalyzes the attachment of phenylalanyl to its cognate transfer RNA molecule in a highly specific two-step reaction. It is an alpha2/beta2 tetramer composed of 2 subunits that belongs to class II aminoacyl-tRNA synthetases. PheT codes the beta subunit and folds as an anti-parallel beta-sheet flanked by alpha-helices. Phenylalanyl-tRNA synthetase binds 2 magnesium ions per tetramer. Localized in the cytoplasm; High confidence in function and specificity.
 
  
 0.771
CAZ94103.1
Conserved hypothetical protein. Features a signal peptide cleaved between the residues 27 and 28. Localized in the periplasm.
       0.769
coaBC
Coenzyme A biosynthesis bifunctional protein coaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
    0.759
recJ
RecJ is a 5'-3' single-strand DNA exonuclease. Required for many types of recombinational events, although the stringency of the requirement for recJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available; Localized in the cytoplasm; High confidence in function and specificity.
 
     0.681
CAZ95386.1
Conserved hypothetical protein; Localized in the cytoplasm.
   
 
 0.644
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.