STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argKLAO/AO transport system kinase ArgK; The ArgK protein acts as an ATPase enzyme and as a kinase, and phosphorylates periplasmic binding proteins involved in the LAO (lysine, arginine, ornithine)/AO transport systems. This phosphorylation results in reduced levels of transport activity of the periplasmic transport systems that include each of the binding proteins; Localized in the cytoplasmic membrane; High confidence in function and specificity. (347 aa)    
Predicted Functional Partners:
mutB
Methylmalonyl-CoA mutase is a heterodimer of a small (alpha) and a large (beta) chain. These two subunits are non-identical, yet structurally related chains. MutB codes the large subunit. Methylmalonyl-CoA mutase is an adenosylcobalamin (vitamin B12) dependent enzyme that catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Localized in the cytoplasm; High confidence in function and specificity.
  
 0.989
CAZ95716.1
Protein that belongs to the Glyoxalase superfamily protein Localized in the cytoplasm; Family membership.
   
 0.969
mutA
Methylmalonyl-CoA mutase is a heterodimer of a small (alpha) and a large (beta) chain. These two subunits are non-identical, yet structurally related chains. MutA codes the small subunit. Methylmalonyl-CoA mutase is an adenosylcobalamin (vitamin B12) dependent enzyme that catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Localized in the cytoplasm; High confidence in function and specificity.
 
  
 0.858
CAZ97076.1
Conserved hypothetical membrane protein; Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.773
arnC2
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, family GT2; ArnC catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the family 2 of the glycosyltransferase (GT2); Contains three C-terminal transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
       0.655
ohrB
OhrB is involved in organic hydroperoxide resistance. It is induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation. Expression is sigma B-dependent. Localized in the cytoplasm; High confidence in function and specificity.
       0.551
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.