STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrA3Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (228 aa)    
Predicted Functional Partners:
msrB1
Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide to methionine. MsrB is specific for methionine-R-sulfoxides. It activates the cysteine or selenocysteine nucleophile through a unique Cys-Arg-Asp/Glu catalytic triad. Regeneration of the active site occurs through a series of thiol-disulfide exchange steps involving another active site Cys residue and thioredoxin. Localized in the cytoplasm; High confidence in function and specificity.
 
 0.988
msrB2
Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide to methionine. MsrB is specific for methionine-R-sulfoxides. It activates the cysteine or selenocysteine nucleophile through a unique Cys-Arg-Asp/Glu catalytic triad. Regeneration of the active site occurs through a series of thiol-disulfide exchange steps involving another active site Cys residue and thioredoxin. Localized in the cytoplasm; High confidence in function and specificity.
 
 0.987
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.787
CAZ97081.1
Conserved hypothetical lipoprotein; Protein containing a bacterial Ig-like domain 1 (Big-1). Big-1 domains (~95 amino acids) are usually present in bacterial adhesion molecules of the intimin/invasin family, involved in pathogenicity. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Conserved hypothetical protein.
       0.504
mroA2
Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; Localized in the cytoplasm; High confidence in function and specificity.
       0.445
ZOBELLIA_1062
Pseudogene; C-terminal fragment of conserved protein found in the PhnB family protein; Possibly localized in the cytoplasm; Conserved hypothetical protein.
   
 0.414
CAZ95381.1
Conserved hypothetical protein; Localized in the cytoplasm.
   
 0.414
CAZ97118.1
Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Belongs to the thioredoxin family; Localized in the cytoplasm; Specificity unclear.
   
 0.414
CAZ98234.1
Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Contains a N-terminal transmembrane helix; Belongs to the thioredoxin family; Localized in the cytoplasmic membrane; Specificity unclear.
   
 0.414
CAZ98582.1
Protein homologous to thioredoxins, glutaredoxins, and protein disulphide isomerases, and shares with them a redox-active disulphide. Localized in the cytoplasm; Family membership.
   
 0.413
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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