STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97092.1ATP:cob(I)alamin (or ATP:corrinoid) adenosyltransferases catalyse the conversion of cobalamin (vitamin B12) into its coenzyme form, adenosylcobalamin (coenzyme B12), or via de novo synthesis. Adenosylcobalamin is required for the ativity of certain enzymes; The metabolic pathway where this enzyme is used is unknown; Belongs to the Cob(I)alamin adenosyltransferase family; Localized in the cytoplasm; High confidence in function and specificity. (193 aa)    
Predicted Functional Partners:
glcG
The protein GlcG is a conserved protein iniatilly found in the glycolate utilization operon. Its exact function is unknown. Signal peptide cleaved between the residues 25 and 26. Localized in the periplasmic space; Function unclear.
     0.927
CAZ97093.1
Conserved hypothetical membrane protein; Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.618
CAZ97094.1
Conserved hypothetical protein; Localized in the cytoplasm.
  
    0.610
mutB
Methylmalonyl-CoA mutase is a heterodimer of a small (alpha) and a large (beta) chain. These two subunits are non-identical, yet structurally related chains. MutB codes the large subunit. Methylmalonyl-CoA mutase is an adenosylcobalamin (vitamin B12) dependent enzyme that catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Localized in the cytoplasm; High confidence in function and specificity.
 
   
 0.531
CAZ97091.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.519
CAZ97096.1
Conserved hypothetical transmembrane protein; Signal peptide cleaved between the residues 22 and 23; Contains five transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
     
 0.495
CAZ97095.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Contains a duplicated ATPase domain; Belongs to the ABC transporter family, EF3 subfamily; Localized in the cytoplasm near of the cytoplasmic membrane by association with a membrane permease component; Family membership.
       0.494
metH-2
Methionine synthase, homocysteine-binding module; Methionine synthase or 5-methyltetrahydrofolate-homocysteine S-methyltransferase catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate; L-homocysteine is bound via the zinc atom; Uses the cobalamin (vitamin B12) and zinc as cofactors; This sequence corresponds to the homocysteine-binding domain (Hcy-binding domain) only; Belongs to the vitamin-B12 dependent methionine synthase family; Localize [...]
 
   
 0.450
mutA
Methylmalonyl-CoA mutase is a heterodimer of a small (alpha) and a large (beta) chain. These two subunits are non-identical, yet structurally related chains. MutA codes the small subunit. Methylmalonyl-CoA mutase is an adenosylcobalamin (vitamin B12) dependent enzyme that catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Localized in the cytoplasm; High confidence in function and specificity.
 
     0.413
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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