STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rluFEnzyme responsible for synthesis of pseudouridine from uracil-2604 in 23S ribosomal RNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Contains a N-terminal S4 RNA-binding domain that probably mediates binding to RNA; Belongs to the pseudouridine synthase RsuA family; localized in the cytoplasm; High confidence in function and specificity. (242 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase is involved in pyrimidine nucleotide metabolism. It catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP. Localized in the cytoplasm; High confidence in function and specificity.
 
  
 0.753
engA-2
GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.717
xthA2
The exonuclease III catalyses the cleavage in the 3'- to 5'-direction on double-stranded DNA to yield nucleoside 5'-phosphates. It also has an endonucleolytic activity near apurinic sites on DNA; Contains an Endonuclease/Exonuclease/phosphatase domains; Belongs to the DNA repair enzymes AP family 1; Localized in the cytoplasm; High confidence in function and specificity.
  
    0.601
xthA1
The exonuclease III catalyses the cleavage in the 3'- to 5'-direction on double-stranded DNA to yield nucleoside 5'-phosphates. It also has an endonucleolytic activity near apurinic sites on DNA; Contains an Endonuclease/ Exonuclease/phosphatase domains; Belongs to the DNA repair enzymes AP family 1; Localized in the cytoplasm; High confidence in function and specificity.
  
    0.601
CAZ97108.1
Conserved hypothetical protein; Contains a C-terminal transmembrane helix; Signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic membrane.
       0.529
CAZ97109.1
This integral membrane protein encompasses two conserved domains (1-444 and 445-786); Contains 22 transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.529
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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