STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97118.1Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Belongs to the thioredoxin family; Localized in the cytoplasm; Specificity unclear. (166 aa)    
Predicted Functional Partners:
CAZ94109.1
Conserved hypothetical membrane protein; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
   
 0.684
CAZ97117.1
Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Belongs to the thioredoxin family; Localized in the cytoplasm; Specificity unclear.
 
   
0.674
dsbD
Thiol:disulfide interchange protein; DsbD, also known as protein-disulfide reductase, is required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps; Uses NAD(P) as cofactor; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
 
 0.576
CAZ98187.1
Conserved protein belonging to the thioredoxin family. Thioredoxins are small proteins of approximately one hundred amino-acid residues which participate in various redox reactions via the reversible oxidation of an active center disulfide bond; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership.
  
 
 0.520
CAZ98097.1
Conserved protein belonging to the DUF179 family. Localized in the cytoplasm; Family membership.
   
 
 0.515
CAZ96539.1
Conserved hypothetical membrane protein; Protein that consists of a SCO1/SenC domain; Belongs to the SCO2/SenC family; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.507
CAZ96021.1
Conserved hypothetical membrane protein; Protein that consists of a SCO1/SenC domain; Contains a N-terminal transmembrane segment; Belongs to the SCO2/SenC family; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.500
bfmBC
The Dihydrolipoyl dehydrogenase is the E3 component of the branched-chain alpha-keto dehydrogenase complex. This complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It is involved in valine, leucine and isoleucine biodegradation. It contains multiple copies of three enzymatic components: branched- chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). The E3 component converts the Protein 6-N-(dihydrolipoyl)lysine to protein 6-N-(lipoyl)lysine. Dihydrolipoyl dehydrogenase is a homodimer, which binds 1 NAD [...]
 
 0.498
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
   
 
 0.484
CAZ97965.1
Conserved hypothetical membrane protein; Protein that consists of a SCO1/SenC domain; Contains a N-terminal transmembrane segment; Belongs to the SCO2/SenC family; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.480
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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