STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
tktBTransketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5- phosphate to an aldose receptor, such as ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. TK provides a link between the Embden-Meyerhof and pentose-phosphate (Non-oxidative phase) pathways; Uses calcium ion as a cofactor and thiamine diphosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity. (317 aa)    
Predicted Functional Partners:
tktA
Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5- phosphate to an aldose receptor, such as ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. TK provides a link between the Embden-Meyerhof and pentose-phosphate (Non-oxidative phase) pathways; Uses calcium ion as a cofactor and thiamine diphosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity.
 0.999
rpeA
Ribulose-phosphate 3-epimerase converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Pentose phosphate pathway; Adopts a a TIM barrel fold; Localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.955
rpiB
Ribose 5-phosphate isomerase B catalyses the conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; Forms a homodimer; Localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.932
talA1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.919
talA2
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.919
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.911
pgiA
Glucose-6-phosphate isomerase is a dimeric enzyme that catalyses the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate in the second step of glycolysis (Embden-Meyerhof pathway) and in oxydative phase of pentose phosphate pathway. PgiA also is involved in the gluconeogenesis and in Pentose phosphate pathway; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the GPI family.
     
 0.907
prsA
Ribose-phosphate pyrophosphokinase converts the D-ribose 5-phosphate to 5-phospho-alpha-D-ribose 1-diphosphate in the Pentose phosphate pathway. Utilized by both the de novo and the salvage pathways by which endogenously formed or exogenously added pyrimidine, purine, or pyridine bases are converted to the corresponding ribonucleoside monophosphates; Localized in the cytoplasm; High confidence in function and specificity.
    
  0.907
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
    
  0.907
fbaB
Fructose-bisphosphate aldolase, class 1; Fructose-bisphosphate aldolase catalyzes the fourth step of the glycolysis (Embden-Meyerhof pathway). It cleaves the hexose D-fructose 1,6-bisphosphate into two trioses sugars: the dihydroxyacetone phosphate (ketone) and the D-glyceraldehyde 3-phosphate (aldehyde); Belongs to the DeoC/LacD aldolase family (Common phosphate binding- site TIM barrel superfamily); Localized in the cytoplasm; High confidence in function and specificity.
    
  0.906
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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