STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CAZ97284.1Sulfatase, family S1-19; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 19; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Family membership. (511 aa)    
Predicted Functional Partners:
idsA3
Iduronate-2-sulfatase, family S1-7; Iduronate-2-sulfatase, called also chondroitinsulfatase is involved in the glycosaminoglycan degradation. It hydrolyzes the 2-sulfate groups from non-reducing-terminal iduronic acid residues in dermatan sulfate, heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 7; Lipoprotein with a signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; High confidence in function and specificity.
 
    
0.838
CAZ97286.1
Conserved protein belonging to the DUF1680 family protein; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein.
       0.642
fgeA
C-alpha-formylglycine-generating protein; Converts newly synthesized inactive sulfatases to their active form by modifying an active site cysteine or serine residue to 3-oxoalanine; Putatively localized in the outer membrane; Specificity unclear.
 
   0.572
CAZ97287.1
Conserved protein belonging to the DUF1680 family protein; Localized in the cytoplasm.
 
     0.462
CAZ97288.1
The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership.
 
     0.431
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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