STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97390.1TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Does not contain of carboxypeptidase regulatory domain. The Plug module (41-152) acts as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership. (665 aa)    
Predicted Functional Partners:
nadR
Nicotinamide-nucleotide adenylyltransferase / Ribosylnicotinamide kinase; Bifunctional enzyme involved in the nicotinate and nicotinamide metabolism possessing both NMN (nicotinamide mononucleotide) adenylytransferase (NMNAT) and Ribosylnicotinamide kinase (RNK) activities. NMNAT is an indispensable activity in the biosynthesis of NAD(+) and NADP(+) synthesizing NAD via the salvage pathway. RNK converts the N-ribosylnicotinamide to nicotinamide ribonucleotide; Localized in the cytoplasm. However, this bifunctional enzyme would loosely associate with the membrane through its interaction [...]
 
     0.940
pnuC2
PnuC is the membrane protein responsible for nicotinamide mononucleotide transport; Contains seven transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
  
 0.904
CAZ97391.1
Conserved protein containing two tetratrico peptide repeats (TPRs). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Localized in the cytoplasm.
       0.709
CAZ94360.1
Conserved hypothetical protein; Localized in the cytoplasm.
  
     0.483
CAZ97392.1
The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership.
       0.479
CAZ98465.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-101) and the Plug module (136-233) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership.
  
    0.453
CAZ96872.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-98) and the Plug module (133-232) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership.
  
    0.450
tonB1
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
   0.450
CAZ97395.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.442
CAZ95545.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (39-113) and the Plug module (129-236) acting as a channel gate; The signal peptide is cleaved between the residues 27 and 28; Family membership.
  
     0.440
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.