| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAZ94397.1 | CAZ94398.1 | ZOBELLIA_324 | ZOBELLIA_325 | Creatinase family protein; Conserved protein belonging to the creatine amidohydrolase family; Localized in the cytoplasm; Family membership. | Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership. | 0.520 |
| CAZ94397.1 | CAZ94399.1 | ZOBELLIA_324 | ZOBELLIA_326 | Creatinase family protein; Conserved protein belonging to the creatine amidohydrolase family; Localized in the cytoplasm; Family membership. | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | 0.492 |
| CAZ94397.1 | CAZ94400.1 | ZOBELLIA_324 | ZOBELLIA_327 | Creatinase family protein; Conserved protein belonging to the creatine amidohydrolase family; Localized in the cytoplasm; Family membership. | Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership. | 0.403 |
| CAZ94397.1 | CAZ94401.1 | ZOBELLIA_324 | ZOBELLIA_328 | Creatinase family protein; Conserved protein belonging to the creatine amidohydrolase family; Localized in the cytoplasm; Family membership. | Conserved hypothetical protein; Localized in the cytoplasm. | 0.467 |
| CAZ94398.1 | CAZ94397.1 | ZOBELLIA_325 | ZOBELLIA_324 | Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership. | Creatinase family protein; Conserved protein belonging to the creatine amidohydrolase family; Localized in the cytoplasm; Family membership. | 0.520 |
| CAZ94398.1 | CAZ94399.1 | ZOBELLIA_325 | ZOBELLIA_326 | Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership. | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | 0.766 |
| CAZ94398.1 | CAZ94400.1 | ZOBELLIA_325 | ZOBELLIA_327 | Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership. | Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership. | 0.705 |
| CAZ94398.1 | CAZ94401.1 | ZOBELLIA_325 | ZOBELLIA_328 | Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership. | Conserved hypothetical protein; Localized in the cytoplasm. | 0.572 |
| CAZ94398.1 | CAZ94402.1 | ZOBELLIA_325 | ZOBELLIA_329 | Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership. | Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; Contains an N-terminal HTH domain of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA and a C-terminal UTRA domain that modulates activity of transcription regulator in response to binding small molecules; Localized in the cytoplasm; Family membership. | 0.581 |
| CAZ94399.1 | CAZ94397.1 | ZOBELLIA_326 | ZOBELLIA_324 | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | Creatinase family protein; Conserved protein belonging to the creatine amidohydrolase family; Localized in the cytoplasm; Family membership. | 0.492 |
| CAZ94399.1 | CAZ94398.1 | ZOBELLIA_326 | ZOBELLIA_325 | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership. | 0.766 |
| CAZ94399.1 | CAZ94400.1 | ZOBELLIA_326 | ZOBELLIA_327 | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership. | 0.765 |
| CAZ94399.1 | CAZ94401.1 | ZOBELLIA_326 | ZOBELLIA_328 | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | Conserved hypothetical protein; Localized in the cytoplasm. | 0.646 |
| CAZ94399.1 | CAZ94402.1 | ZOBELLIA_326 | ZOBELLIA_329 | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; Contains an N-terminal HTH domain of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA and a C-terminal UTRA domain that modulates activity of transcription regulator in response to binding small molecules; Localized in the cytoplasm; Family membership. | 0.653 |
| CAZ94399.1 | CAZ94404.1 | ZOBELLIA_326 | ZOBELLIA_331 | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership. | 0.406 |
| CAZ94399.1 | etfA | ZOBELLIA_326 | ZOBELLIA_867 | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | Electron transfer flavoprotein, alpha subunit; The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various dehydrogenases. In Bacteria, ETFs are produced under specific growth conditions, receiving electrons only from the oxidation of specific substrates. ETFs are heterodimeric proteins composed of an alpha and beta subunit, and contain an FAD cofactor and an AMP molecule. EtfA codes the alpha subunit that participate, with the alpha subunit, to the binding of the FAD molecule; Localized in the cytoplasm; High confidence in function and specificity. | 0.433 |
| CAZ94399.1 | etfB | ZOBELLIA_326 | ZOBELLIA_866 | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | Electron transfer flavoprotein, beta subunit; The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various dehydrogenases. In Bacteria, ETFs are produced under specific growth conditions, receiving electrons only from the oxidation of specific substrates. ETFs are heterodimeric proteins composed of an alpha and beta subunit, and contain an FAD cofactor and an AMP molecule. EtfB codes the beta subunit that binds the AMP molecule; Localized in the cytoplasm; High confidence in function and specificity. | 0.445 |
| CAZ94400.1 | CAZ94397.1 | ZOBELLIA_327 | ZOBELLIA_324 | Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership. | Creatinase family protein; Conserved protein belonging to the creatine amidohydrolase family; Localized in the cytoplasm; Family membership. | 0.403 |
| CAZ94400.1 | CAZ94398.1 | ZOBELLIA_327 | ZOBELLIA_325 | Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership. | Sugar kinase; Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership. | 0.705 |
| CAZ94400.1 | CAZ94399.1 | ZOBELLIA_327 | ZOBELLIA_326 | Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership. | FAD dependent oxidoreductase; Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear. | 0.765 |