STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CAZ97440.1Peptidase family M48 contains metalloendopeptidases. This peptidase contains a single catalytic zinc ion tetrahedrally co-ordinated by two histidines within an HEXXH motif, an as yet undetermined third residue and water. The glutamate within the HEXXH motif is assumed to be a catalytic residue. Localized in the cytoplasm; Specificity unclear. (496 aa)    
Predicted Functional Partners:
CAZ97439.1
Probably a cytoplasmic protein.
 
   
 0.943
CAZ97435.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Lipoprotein signal peptide cleaved between the residues 23 and 24; Contains four N-terminal tetratrico peptide repeats (TPR) and one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
     0.855
CAZ98756.1
Glycoside hydrolase, family GH115; Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety; Belongs to the family 115 of the glycoside hydrolases; Signal peptide cleaved between the residues 26 and 27; Putatively localized in the periplasmic space; Conserved hypothetical protein.
  
     0.763
CAZ97438.1
Probably a cytoplasmic protein.
       0.734
CAZ95611.1
Non-peptidase protein, Family M29; This protein belongs to the family 29 of the metallopeptidases, but lacks some of the catalytic or metal-binding residues; Localized in the cytoplasm; Function unclear.
  
   
 0.716
CAZ95608.1
Permease belonging to the Nucleobase Cation Symporter-1 (NCS1) family, which includes transporters for purines, pyrimidines and allantoin. It functions in uptake by substrate:H+ symport mechanism; Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear.
  
     0.711
CAZ95031.1
Conserved hypothetical membrane protein; Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.701
CAZ97653.1
Sulfatase, family S1-20; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; Family membership.
  
     0.658
CAZ95669.1
Conserved hypothetical periplasmic protein; Contains two central TPR motifs and a C-terminal transglutaminase-like domain; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein.
 
     0.630
CAZ97436.1
The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership.
 
     0.629
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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