STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdsA1Mucin-desulfating sulfatase, family S1-11; Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Specificity unclear. (539 aa)    
Predicted Functional Partners:
CAZ94406.1
Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Hypothetical protein.
       0.727
CAZ94407.1
Hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Hypothetical protein.
       0.505
CAZ94409.1
Sulfatase, family S1-16; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Putative lipoprotein with a signal peptide cleaved between the residues 18 and 19. Possibly localized in the outer membrane; Family membership.
 
    
0.482
CAZ94404.1
RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership.
       0.407
CAZ95056.1
Sulfatase, family S1-23; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 23; Contains a N-terminal transmembrane segment, Localized in the cytoplasmic membrane; Family membership.
  
   
0.400
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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