STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97585.1Sulfatase, family S1-23; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 23; Possible signal peptide of lipoprotein cleaved between the residues 23 and 24; Putatively localized in the outer membrane; Family membership. (492 aa)    
Predicted Functional Partners:
CAZ97584.1
Carbohydrate esterase, family CE10; Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 10 of the carbohydrate esterases (CE10); Signal peptide cleaved between residues 19 and 20; Localized in the periplasmic space; Specificity unclear.
   0.816
mdsA3
Mucin-desulfating sulfatase, family S1-11; Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Signal peptide cleaved between the residues 22 and 23; Seems localized in the periplasmic space; Specificity unclear.
 
   
0.710
CAZ97588.1
Beta-helix fold protein; Protein that likely adopts a right handed parallel beta-helix fold; Contains a C-terminal PDZ domain responsible of protein-protein interaction by binding either the carboxyl-terminal sequences of proteins or internal peptide sequences suggesting that it could be a signaling protein; Prokaryotic lipoprotein signal peptide cleaved between 19 and 20; Localized in the outer membrane; Conserved hypothetical protein.
 
    0.600
uglA1
Unsaturated glucuronyl hydrolase, family GH88; Unsaturated glucuronyl hydrolase is involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. UglA catalyzes the hydrolysis of oligosaccharides with unsaturated uronic acids at the nonreducing terminal, to a sugar or an amino sugar, and an unsaturated uronic acid, which is nonenzymatically converted immediately to alpha-keto acid; Belongs to the family 88 of the glycoside hydrolases (GH88); Signal peptide cleaved between residues 22 and 23. Localized in the periplasmic space; Specificity unclear.
 
     0.577
alfA5
Alpha-L-fucosidase, family GH29 / Acetylesterase; Modular protein with a N-terminal alpha-L-fucosidase module belonging to the family 29 of the glycoside hydrolases (GH29) and a C-terminal acetyl esterase domain belonging to the lipase-GDSL family which includes families 3 and 12 of the carbohydrate esterases (CE3/CE12); Catalytic activities: an alpha-L-fucoside + H2O = L-fucose + an alcohol and an acetic ester + H2O = an alcohol + acetate; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Specificity unclear.
 
     0.538
CAZ97599.1
Sulfatase, family S1-28; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 28; Putative lipoprotein with a signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; Family membership.
 
   
0.464
CAZ97587.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 32 and 33; Localized in the periplasmic space; Conserved hypothetical protein.
       0.452
CAZ97593.1
Sulfatase, family S1-17; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Contains a N-terminal transmembrane helix; Possibly localized in the cytoplasmic membrane; Family membership.
 
    
0.451
fgeA
C-alpha-formylglycine-generating protein; Converts newly synthesized inactive sulfatases to their active form by modifying an active site cysteine or serine residue to 3-oxoalanine; Putatively localized in the outer membrane; Specificity unclear.
 
   0.438
CAZ97578.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 24 and 25; Possibly localized in the outer membrane; Family membership.
  
     0.419
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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